Recent radiation techniques, such as intensity-modulated radiotherapy, minimize such adverse effects by decreasing the dose of radiation received by the normal surrounding structures[ 86 ]. Malignant epithelial tumors of the anal canal. The current treatment options in AC are well defined in locally advanced and metastatic disease with acceptable results. At least 4 weeks since major surgery, chemotherapy, investigational agent or radiation therapy. Known locally advanced, locally recurrent or metastatic colorectal adenocarcinoma not curable by surgery or amenable to radiation therapy with curative intent or previously treated for advanced disease.
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Anal cancer treatment: Current status and future perspectives
Treatment of HIV-associated invasive anal cancer with combined chemoradiation. Chemoradiation for the treatment of epidermoid anal cancer: Cancer of the anal canal. To assess the toxicity of SB in patients with locally advanced, recurrent or metastatic hepatocellular carcinoma, as well as early progression rate, and, if responses are observed, response duration. No evidence of perforation or clinical obstruction of the bowel. These adverse effects usually require treatment breaks, which decrease the efficacy of radiation.